Induced Pluripotent Stem Cells (iPSC) Core

Overview of Services

About Us:
Induced pluripotent stem cells are a novel resource for studying disease mechanisms and advancing personalized medicine, driving the demand for a dedicated Induced Pluripotent Stem Cells (iPSC) Core at Nationwide Children's Hospital.
Our goal is to generate and share iPSC lines with investigators not only at Nationwide Children's and The Ohio State University, but throughout Ohio and across the country. Our experienced staff are here to help during every step of your project, ranging from PBMC isolation and reprogramming to enrichment training and obtaining MTAs. We also provide characterization, cryopreservation and differentiation services on newly generated iPSC lines and existing lines from a congenital heart disease iPSC biorepository.

Services We Offer:
Peripheral blood mononuclear cell (PBMC) isolation
Human iPSC line generation and cryopreservation
Quality control of iPSC lines including karyotyping, pluripotency marker expression, in vitro germ layer differentiation, cell line authentication, and mycoplasma contamination testing
Cardiomyocyte and Endothelial cell differentiation
Enrichment training for iPSC culture and differentiation

Leadership

Location and hours of operation

Links and Resources

1. Induced Pluripotent Stem Cells Core | Nationwide Children's Hospital

Contacts

Map